LIPIPRES

LIPIPRES contains Atorvastatin which is a member of the drug class known as statins. It is used for lowering cholesterol. Atorvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. It is the most trusted for the Prevention of Cardiovascular Disease & Hyperlipidemia.

COMPOSITION:

Atorvastatin 10 mg Tablets

MODE OF ACTION:

LIPIPRES is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonate, a precursor of sterols, including cholesterol. In animal models, Lipipres lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and by increasing the number of hepatic LDL receptors on the cell surface to enhance uptake and catabolism of LDL; Lipipres also reduces LDL production and the number of LDL particles.

INDICATIONS

Treatment of hypercholesterolemia, including hyperlipidemia, hyperlipoproteinemia, or hypertriglyceridemia, as an adjunct to dietary control, for the purpose of reducing the risk of cardiovascular events.

DOSAGE

Adults – Initially, 10 to 20 mg PO once daily. May start at 40 mg PO once daily in patients requiring greater than 45% LDL-reduction. The dosage range is 10 to 80 mg PO once daily (mean LDL reduction range: 43% to 60% LDL); Children and Adolescents 10 years and older – 10 mg PO once daily initially. The dosage may be increased to 20 mg/day PO after four weeks or longer if necessary to attain the target LDL and lipid goals.; Children 6 to 9 years – 5 mg PO once daily increased to 10 mg PO once daily after four weeks if the goal LDL of less than 130 mg/dL was not reached was used in a small, short-term study of pediatric patients with heterozygous familial hypercholesterolemia.

DISCLAIMER

This information is for the medical professionals & registered medical practitioners only. This product must be consumed with the valid prescription of registered medical practitioners.*Images/Pack are for representation purpose only.