AMIGRAF (Tacrolimus) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient’s immune system and so the risk of organ rejection. Tacrolimus is used together with other medicines in people who have had a heart, kidney, liver, or lung transplant. Tacrolimus weakens immune system to prevent the body from “rejecting” the transplanted organ.
MOFICEPT, Mycophenolate Mofetil also known as MMF is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants.
MOFICEPT-S (Mycophenolate Sodium 360 mg Tablet) belongs to a group of medicines known as immunosuppressive agents. Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until it reaches the small intestine. It is prescribed to transplant recipients to prevent organ rejection.
CYTOMEGA, Valganciclovir is used in adults to prevent infection with cytomegalovirus (CMV) that may occur after an organ transplant (heart, kidney, or pancreas). It is actually a prodrug for ganciclovir. After oral administration, it rapidly convert into ganciclovir by intestinal and hepatic esterases. CYTOMEGA is also used to treat CMV retinitis in people who have acquired immunodeficiency syndrome (AIDS).
SIROTOR, Sirolimus is also known as rapamycin, is a macrocyclic lactone antibiotic and an mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.